#27: Thomas Frist Jr. and Family – Tennessee

In Tennessee, Thomas Frist Jr. and his family boast a whopping fortune of $21.1 billion. Transitioning from an Air Force flight surgeon to a healthcare magnate, Frist founded the Hospital Corp. of America, dramatically improving healthcare and enriching himself.

Starting with modest origins, their hospital company now manages 185 hospitals and 1,800 care sites across 21 states and London, underscoring the immense growth and success of their healthcare empire.